Sandra Steingard,
M.D.
September 8, 2013
The Wunderink study
has been discussed here in other blogs (here,
here, and here). In brief, using a randomized control design, Wunderink
found that in adults diagnosed with a psychotic disorder continuous use of
neuroleptics was associated with worse functional outcomes than intermittent use. Higher doses were associated with worse
outcomes than lower ones.
These days
neuroleptic drugs are widely promoted to treat depression and they are often
used “off-label” to treat behavioral problems in children. They are among the most widely prescribed
drugs; given that “schizophrenia” affects 1% of the population, it is clear
that many individuals – adults and children – who do not have this diagnosis
are prescribed these drugs.
Is the Wunderink
study relevant to those who do not experience psychosis? >More of Dr.Sandra Steingard's report<
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